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Human polymorphism at microRNAs and microRNA target sites

MicroRNAs (miRNAs) function as endogenous translational repressors of protein-coding genes in animals by binding to target sites in the 3′ UTRs of mRNAs. Because a single nucleotide change in the sequence of a target site can affect miRNA regulation, naturally occurring SNPs in target sites are cand...

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Autori principali: Saunders, Matthew A., Liang, Han, Li, Wen-Hsiung
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805605/
https://ncbi.nlm.nih.gov/pubmed/17360642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611347104
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