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Spatial genome organization in the formation of chromosomal translocations

Chromosomal translocations and genomic instability are universal hallmarks of tumor cells. While the molecular mechanisms leading to the formation of translocations are rapidly being elucidated, a cell biological understanding of how chromosomes undergo translocations in the context of the cell nucl...

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Detalhes bibliográficos
Main Authors: Meaburn, Karen J., Misteli, Tom, Soutoglou, Evi
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805052/
https://ncbi.nlm.nih.gov/pubmed/17137790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2006.10.008
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