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Effect of ribavirin on macromolecular synthesis in vesicular stomatitis virus-infected cells.

Ribavirin at 200 micrograms/ml inhibited vesicular stomatitis virus (VSV) growth in Chinese hamster ovary (CHO) cells by 2.5 logs. To determine the mechanism of this inhibition, viral macromolecular synthesis was examined. VSV primary transcription remained unaffected, but overall VSV RNA synthesis...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Toltzis, P, Huang, A S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1010
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