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Effect of ribavirin on macromolecular synthesis in vesicular stomatitis virus-infected cells.

Ribavirin at 200 micrograms/ml inhibited vesicular stomatitis virus (VSV) growth in Chinese hamster ovary (CHO) cells by 2.5 logs. To determine the mechanism of this inhibition, viral macromolecular synthesis was examined. VSV primary transcription remained unaffected, but overall VSV RNA synthesis...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Toltzis, P, Huang, A S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1986
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1010
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