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Effect of ribavirin on macromolecular synthesis in vesicular stomatitis virus-infected cells.

Ribavirin at 200 micrograms/ml inhibited vesicular stomatitis virus (VSV) growth in Chinese hamster ovary (CHO) cells by 2.5 logs. To determine the mechanism of this inhibition, viral macromolecular synthesis was examined. VSV primary transcription remained unaffected, but overall VSV RNA synthesis...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Toltzis, P, Huang, A S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180493/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015012/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.6.1010
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