Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits.

Itraconazole and fluconazole, two new triazoles, were examined for their antifungal activity in rabbits. Fluconazole easily crossed the blood-cerebrospinal fluid barrier, and active drug was eliminated in high concentrations in the urine. On the other hand, itraconazole did not cross the blood-cereb...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Perfect, J R, Savani, D V, Durack, D T
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1986
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180445/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.4.579
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