In vitro and in vivo comparisons of amphotericin B and N-D-ornithyl amphotericin B methyl ester.
N-D-Ornithyl amphotericin B methyl ester (N-D-ornithyl AmE) has a lower toxicity for animals than does amphotericin B (AmB), and peak serum levels can be achieved that are fourfold higher than those obtained with an equivalent dose of AmB. However, N-D-ornithyl AmE has one-fourth the in vitro activi...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC176265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3994345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.3.302 |
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