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In Vitro Activity of the Oxazolidinone RWJ-416457 against Linezolid-Resistant and -Susceptible Staphylococci and Enterococci
RWJ-416457, a novel oxazolidinone, had modal MICs of 0.5 to 1 μg/ml for linezolid-susceptible staphylococci and enterococci, versus linezolid MICs for these organisms of 1 or 2 μg/ml. RWJ-416457 MICs for mutants with 23S rRNA mutations were 2 to 32 μg/ml, versus linezolid MICs of 8 to 64 μg/ml; actu...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1803128/ https://ncbi.nlm.nih.gov/pubmed/17210773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01347-06 |
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