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In vitro activity of tedizolid against linezolid-resistant staphylococci and enterococci

The tedizolid MIC of 27 clinical isolates of linezolid-resistant staphylococci and enterococci was determined. Tedizolid MICs were ≥1 μg/mL and were 4- to 32-fold lower than those of linezolid. Linezolid resistance mechanisms included G2576T 23S rRNA gene and rplC and rplD mutations.

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Détails bibliographiques
Publié dans:Diagn Microbiol Infect Dis
Auteurs principaux: Silva-Del Toro, Stephanie L., Greenwood-Quaintance, Kerryl E., Patel, Robin
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067670/
https://ncbi.nlm.nih.gov/pubmed/26971179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2016.02.008
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