In Vitro Antibacterial Activity of the Pyrrolopyrazolyl-Substituted Oxazolidinone RWJ-416457

RWJ-416457, an investigational pyrrolopyrazolyl-substituted oxazolidinone, inhibited the growth of linezolid-susceptible staphylococci, enterococci, and streptococci at concentrations of ≤4 μg/ml, generally exhibiting two- to fourfold-greater potency than that of linezolid. Time-kill studies demonst...

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Autors principals: Foleno, Barbara D., Abbanat, Darren, Goldschmidt, Raul M., Flamm, Robert K., Paget, Steve D., Webb, Glenda C., Wira, Ellyn, Macielag, Mark J., Bush, Karen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797661/
https://ncbi.nlm.nih.gov/pubmed/17101672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01017-06
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