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Glutamine depletion potentiates leucocyte-dependent inflammatory events induced by carrageenan or Clostridium difficile toxin A in rats

This research investigated the effect of glutamine (Gln) depletion on leucocyte-dependent inflammatory events. Rats were treated intraperitoneally, 16 hr prior to the peak of every parameter evaluated, with either 0·9% NaCl, methionine-sulphoximine (MSO, an inhibitor of endogenous Gln synthesis, 25...

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Detalhes bibliográficos
Main Authors: Nascimento, Silvia B, Sousa, Romualdo B, Martins, Marcos Jullian B, Souza Gomes, Antoniella, Souza, Marcellus Henrique L P, Guerrant, Richard L, Cunha, Fernando Q, Ribeiro, Ronaldo A, Brito, Gerly A C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802418/
https://ncbi.nlm.nih.gov/pubmed/16236122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02232.x
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