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Dysregulated luminal bacterial antigen-specific T-cell responses and antigen-presenting cell function in HLA-B27 transgenic rats with chronic colitis

HLA-B27/β2 microglobulin transgenic (TG) rats spontaneously develop T-cell-mediated colitis when colonized with normal commensal bacteria, but remain disease-free under germ-free conditions. We investigated regulation of in vitro T-cell responses to enteric bacterial components. Bacterial lysates pr...

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Hlavní autoři: Qian, Bi-Feng, Tonkonogy, Susan L, Hoentjen, Frank, Dieleman, Levinus A, Sartor, R Balfour
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802408/
https://ncbi.nlm.nih.gov/pubmed/16108823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02206.x
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