Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats

Germ-free HLA-B27 transgenic (TG) rats do not develop colitis, but colonization with specific pathogen-free (SPF) bacteria induces colitis accompanied by immune activation. To study host-dependent immune responses to commensal caecal bacteria we investigated cytokine profiles in mesenteric lymph nod...

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Autores principales: DIELEMAN, L A, HOENTJEN, F, QIAN, B-F, SPRENGERS, D, TJWA, E, TORRES, M F, TORRICE, C D, SARTOR, R B, TONKONOGY, S L
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
Materias:
Animal Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808999/
https://ncbi.nlm.nih.gov/pubmed/15030511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02410.x
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