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Allele-specific histone modifications regulate expression of the Dlk1-Gtl2 imprinted domain

Dlk1 and Gtl2 are reciprocally expressed imprinted genes located on mouse chromosome 12. The Dlk1-Gtl2 locus carries three differentially methylated regions (DMRs), which are methylated only on the paternal allele. Of these, the intergenic (IG) DMR, located 12 kb upstream of Gtl2 is required for pro...

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Detalhes bibliográficos
Main Authors: Carr, Michael S., Yevtodiyenko, Aleksey, Schmidt, Claudia L., Schmidt, Jennifer V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802099/
https://ncbi.nlm.nih.gov/pubmed/17126526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2006.10.005
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