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The Dlk1 and Gtl2 genes are linked and reciprocally imprinted

Genes subject to genomic imprinting exist in large chromosomal domains, probably reflecting coordinate regulation of the genes within a cluster. Such regulation has been demonstrated for the H19, Igf2, and Ins2 genes that share a bifunctional imprinting control region. We have identified the Dlk1 ge...

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Autors principals: Schmidt, Jennifer V., Matteson, Paul G., Jones, Beverly K., Guan, Xiao-Juan, Tilghman, Shirley M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316857/
https://ncbi.nlm.nih.gov/pubmed/10950864
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