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Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region

BACKGROUND: The Dlk1 and Gtl2 genes define a region of mouse chromosome 12 that is subject to genomic imprinting, the parental allele-specific expression of a gene. Although imprinted genes play important roles in growth and development, the mechanisms by which imprinting is established and maintain...

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Hlavní autoři: Steshina, Ekaterina Y, Carr, Michael S, Glick, Elena A, Yevtodiyenko, Aleksey, Appelbe, Oliver K, Schmidt, Jennifer V
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609179/
https://ncbi.nlm.nih.gov/pubmed/17014736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-7-44
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