Loss of α-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

Microtubules function as molecular tracks along which motor proteins transport a variety of cargo to discrete destinations within the cell. The carboxyl termini of α- and β-tubulin can undergo different posttranslational modifications, including polyglutamylation, which is particularly abundant with...

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Hlavní autoři: Ikegami, Koji, Heier, Robb L., Taruishi, Midori, Takagi, Hiroshi, Mukai, Masahiro, Shimma, Shuichi, Taira, Shu, Hatanaka, Ken, Morone, Nobuhiro, Yao, Ikuko, Campbell, Patrick K., Yuasa, Shigeki, Janke, Carsten, MacGregor, Grant R., Setou, Mitsutoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802010/
https://ncbi.nlm.nih.gov/pubmed/17360631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611547104
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