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Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region.

Disequilibrium between genetic markers is expected to decline monotonically with recombinational map distance. We present evidence from the HLA class II region that seems to violate this principle. Pairwise disequilibrium values were calculated from six loci ranging in physical separation from 15 kb...

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Bibliografische gegevens
Hoofdauteurs: Klitz, W, Stephens, J C, Grote, M, Carrington, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801434/
https://ncbi.nlm.nih.gov/pubmed/8533774
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