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Selection, Hitchhiking and Disequilibrium Analysis at Three Linked Loci with Application to Hla Data

The HLA system has been extensively studied from an evolutionary perspective. Although it is clear that selection has acted on the genes in the HLA complex, the nature of this selection has yet to be fully clarified. A study of constrained disequilibrium values is presented that is applicable to HLA...

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Detalhes bibliográficos
Main Authors: Robinson, W. P., Cambon-Thomsen, A., Borot, N., Klitz, W., Thomson, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1204759/
https://ncbi.nlm.nih.gov/pubmed/1752429
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