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Effects of urinary pH on renal interactions between probenecid and cefsulodin in rabbits.

The effect of urinary pH on renal interaction of cefsulodin and probenecid was tested in rabbits. Probenecid was reabsorbed in acidic urine (fractional excretion [FE] = 8 +/- 4%) and secreted in alkaline urine (FE = 492 +/- 258%). Renal excretion of cefsulodin alone was not affected by the urinary p...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Dromer, F, Contrepois, A, Brion, N, Klein, C, Carbon, C
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1985
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4004198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.660
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