Effects of urinary pH on renal interactions between probenecid and cefsulodin in rabbits.

The effect of urinary pH on renal interaction of cefsulodin and probenecid was tested in rabbits. Probenecid was reabsorbed in acidic urine (fractional excretion [FE] = 8 +/- 4%) and secreted in alkaline urine (FE = 492 +/- 258%). Renal excretion of cefsulodin alone was not affected by the urinary p...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Dromer, F, Contrepois, A, Brion, N, Klein, C, Carbon, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4004198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.660
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