Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome.

Germ-line mutations of the tumor-suppressor gene p53 have been observed in some families with the Li-Fraumeni syndrome (LFS), a familial cancer syndrome in which affected relatives develop a diverse set of early-onset malignancies including breast carcinoma, sarcomas, and brain tumors. The analysis...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Frebourg, T, Barbier, N, Yan, Y X, Garber, J E, Dreyfus, M, Fraumeni, J, Li, F P, Friend, S H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801151/
https://ncbi.nlm.nih.gov/pubmed/7887414
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares