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Molecular analysis of the acid sphingomyelinase deficiency in a family with an intermediate form of Niemann-Pick disease.

A novel point mutation in the lysosomal acid sphingomyelinase gene has been identified in the recently reported Serbian family with a clinically and biochemically atypical intermediate form of Niemann-Pick disease. The mutation was a T1171-->G transversion resulting in substitution of glycine for...

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Autors principals: Ferlinz, K, Hurwitz, R, Weiler, M, Suzuki, K, Sandhoff, K, Vanier, M T
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801117/
https://ncbi.nlm.nih.gov/pubmed/7762557
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