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Occurrence of two molecular forms of human acid sphingomyelinase.

Human acid sphingomyelinase (ASM) hydrolyses sphingomyelin to ceramide and phosphocholine. Metabolic studies on COS-1 cells transfected with ASM cDNA revealed the occurrence of an enzymically inactive precursor which is differentially processed to two predominant native glycoprotein forms: a 70 kDa...

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Autors principals: Ferlinz, K, Hurwitz, R, Vielhaber, G, Suzuki, K, Sandhoff, K
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137065/
https://ncbi.nlm.nih.gov/pubmed/8053910
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