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Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo
Plasma procarboxypeptidase B (proCPB) is activated by the endothelial thrombin-prothrombomodulin complex. Activated (CPB) functions as a fibrinolysis inhibitor, but it may play a broader role by inactivating inflammatory mediators. To test this hypothesis, C5a-induced alveolitis was studied in wild-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801069/ https://ncbi.nlm.nih.gov/pubmed/17105819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-012567 |
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