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Evidence for the multimeric structure of ferroportin

Ferroportin (Fpn) (IREG1, SLC40A1, MTP1) is an iron transporter, and mutations in Fpn result in a genetically dominant form of iron overload disease. Previously, we demonstrated that Fpn is a multimer and that mutations in Fpn are dominant negative. Other studies have suggested that Fpn is not a mul...

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Bibliographic Details
Main Authors: De Domenico, Ivana, Ward, Diane McVey, Musci, Giovanni, Kaplan, Jerry
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801059/
https://ncbi.nlm.nih.gov/pubmed/17077321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-032516
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