Single-dose pharmacokinetics of imipenem-cilastatin in neonates.

The single-dose pharmacokinetics of imipenem (N-formimidoyl thienamycin), a beta-lactam antibiotic, used in combination with cilastatin, a renal dehydropeptidase I inhibitor, were evaluated in 10 neonates 1 to 8 days of age. The imipenem-cilastatin combination was given intravenously over a 15-min p...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gruber, W C, Rench, M A, Garcia-Prats, J A, Edwards, M S, Baker, C J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1985
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3859243/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.27.4.511
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