VHL Promotes E2 Box-Dependent E-Cadherin Transcription by HIF-Mediated Regulation of SIP1 and Snail

The product of the von Hippel-Lindau gene (VHL) acts as the substrate-recognition component of an E3 ubiquitin ligase complex that ubiquitylates the catalytic α subunit of hypoxia-inducible factor (HIF) for oxygen-dependent destruction. Although emerging evidence supports the notion that deregulated...

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Autores principales: Evans, Andrew J., Russell, Ryan C., Roche, Olga, Burry, T. Nadine, Fish, Jason E., Chow, Vinca W. K., Kim, William Y., Saravanan, Arthy, Maynard, Mindy A., Gervais, Michelle L., Sufan, Roxana I., Roberts, Andrew M., Wilson, Leigh A., Betten, Mark, Vandewalle, Cindy, Berx, Geert, Marsden, Philip A., Irwin, Meredith S., Teh, Bin T., Jewett, Michael A. S., Ohh, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800649/
https://ncbi.nlm.nih.gov/pubmed/17060462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00892-06
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