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Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells
Loss of E-cadherin (E-cad) triggers invasion, metastasis, and dedifferentiation in various epithelial carcinomas. Recently, it has been reported that two transcription factors, Snail and SIP1 (Smad interacting protein 1), directly repress transcription of the E-cad gene by binding E-box on E-cad pro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409652/ https://ncbi.nlm.nih.gov/pubmed/15026811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601685 |
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