Acetaldehyde dissociates the PTP1B–E-cadherin–β-catenin complex in Caco-2 cell monolayers by a phosphorylation-dependent mechanism

Interactions between E-cadherin, β-catenin and PTP1B (protein tyrosine phosphatase 1B) are crucial for the organization of AJs (adherens junctions) and epithelial cell–cell adhesion. In the present study, the effect of acetaldehyde on the AJs and on the interactions between E-cadherin, β-catenin and...

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Detalhes bibliográficos
Main Authors: Sheth, Parimal, Seth, Ankur, Atkinson, Katherine J., Gheyi, Tarun, Kale, Gautam, Giorgianni, Francesco, Desiderio, Dominic M., Li, Chunying, Naren, Anjaparavanda, Rao, Radhakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798442/
https://ncbi.nlm.nih.gov/pubmed/17087658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060665
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