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Hydrogen peroxide activates focal adhesion kinase and c-Src by a phosphatidylinositol 3 kinase-dependent mechanism and promotes cell migration in Caco-2 cell monolayers

Recent studies showed that c-Src and phosphatidylinositol 3 (PI3) kinase mediate the oxidative stress-induced disruption of tight junctions in Caco-2 cell monolayers. The present study evaluated the roles of PI3 kinase and Src kinase in the oxidative stress-induced activation of focal adhesion kinas...

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Главные авторы: Basuroy, Shyamali, Dunagan, Mitzi, Sheth, Parimal, Seth, Ankur, Rao, R. K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904105/
https://ncbi.nlm.nih.gov/pubmed/20378826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00368.2009
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