Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis: Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacy

Members of the fluoroquinolone class are being actively evaluated for inclusion in tuberculosis chemotherapy regimens, and we sought to determine the best in vitro and pharmacodynamic predictors of in vivo efficacy in mice. MICs for Mycobacterium tuberculosis H37Rv were 0.1 mg/liter (sparfloxacin [S...

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Detaylı Bibliyografya
Asıl Yazarlar: Shandil, Radha K., Jayaram, Ramesh, Kaur, Parvinder, Gaonkar, Sheshagiri, Suresh, B. L., Mahesh, B. N., Jayashree, R., Nandi, Vrinda, Bharath, Sowmya, Balasubramanian, V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797767/
https://ncbi.nlm.nih.gov/pubmed/17145798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00414-06
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