Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis: Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacy

Members of the fluoroquinolone class are being actively evaluated for inclusion in tuberculosis chemotherapy regimens, and we sought to determine the best in vitro and pharmacodynamic predictors of in vivo efficacy in mice. MICs for Mycobacterium tuberculosis H37Rv were 0.1 mg/liter (sparfloxacin [S...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shandil, Radha K., Jayaram, Ramesh, Kaur, Parvinder, Gaonkar, Sheshagiri, Suresh, B. L., Mahesh, B. N., Jayashree, R., Nandi, Vrinda, Bharath, Sowmya, Balasubramanian, V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2007
विषय:
Experimental Therapeutics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797767/
https://ncbi.nlm.nih.gov/pubmed/17145798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00414-06
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