Aerosol Infection Model of Tuberculosis in Wistar Rats

We explored suitability of a rat tuberculosis aerosol infection model for investigating the pharmacodynamics of new antimycobacterial agents. Infection of rats via the aerosol route led to a reproducible course of M. tuberculosis infection in the lungs. The pulmonary bacterial load increased logarit...

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Detalhes bibliográficos
Main Authors: Gaonkar, Sheshagiri, Bharath, Sowmya, Kumar, Naveen, Balasubramanian, V., Shandil, Radha K.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842889/
https://ncbi.nlm.nih.gov/pubmed/20339504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/426035
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