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Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs

A number of anticancer and antiparasitic drugs are postulated to target the polyamine biosynthetic pathway and polyamine function, but the exact mode of action of these compounds is still being elucidated. To establish whether polyamine analogs specifically target enzymes of the polyamine pathway, a...

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Detalhes bibliográficos
Main Authors: Roberts, Sigrid C., Jiang, Yuqui, Gasteier, Judith, Frydman, Benjamin, Marton, Laurence J., Heby, Olle, Ullman, Buddy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797743/
https://ncbi.nlm.nih.gov/pubmed/17116678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01193-06
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