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Fitness Costs of Fluoroquinolone Resistance in Streptococcus pneumoniae

The fitness cost of the genes responsible for resistance to fluoroquinolones in clinical isolates of Streptococcus pneumoniae were estimated in vitro in a common genetic background. Naturally occurring parC, parE, and gyrA loci containing mutations in the quinolone-resistance-determining regions wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rozen, Daniel E., McGee, Lesley, Levin, Bruce R., Klugman, Keith P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797730/
https://ncbi.nlm.nih.gov/pubmed/17116668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01161-06
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