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Fitness of Streptococcus pneumoniae Fluoroquinolone-Resistant Strains with Topoisomerase IV Recombinant Genes

The low prevalence of ciprofloxacin-resistant (Cp(r)) Streptococcus pneumoniae isolates carrying recombinant topoisomerase IV genes could be attributed to a fitness cost imposed by the horizontal transfer, which often implies the acquisition of larger-than-normal parE-parC intergenic regions. A stud...

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Detalhes bibliográficos
Main Authors: Balsalobre, Luz, de la Campa, Adela G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258501/
https://ncbi.nlm.nih.gov/pubmed/18160515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00731-07
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