Inhibition of Anthrax Protective Antigen Outside and Inside the Cell

In the course of Bacillus anthracis infection, B. anthracis lethal factor (LF) and edema factor bind to a protective antigen (PA) associated with cellular receptors ANTXR1 (TEM8) or ANTXR2 (CMG2), followed by internalization of the complex via receptor-mediated endocytosis. A new group of potential...

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Detalhes bibliográficos
Main Authors: Backer, Marina V., Patel, Vimal, Jehning, Brian T., Claffey, Kevin P., Karginov, Vladimir A., Backer, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797656/
https://ncbi.nlm.nih.gov/pubmed/17074791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00983-06
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