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RNA-mediated destabilization of the σ(70) region 4/β flap interaction facilitates engagement of RNA polymerase by the Q antiterminator
The bacterial RNA polymerase (RNAP) holoenzyme consists of a catalytic core enzyme (α(2)ββ'ω) complexed with a σ factor that is required for promoter-specific transcription initiation. During early elongation, the stability of interactions between σ(70) (the primary sigma factor in Escherichia...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797609/ https://ncbi.nlm.nih.gov/pubmed/17081994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.09.014 |
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