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RNA-mediated destabilization of the σ(70) region 4/β flap interaction facilitates engagement of RNA polymerase by the Q antiterminator

The bacterial RNA polymerase (RNAP) holoenzyme consists of a catalytic core enzyme (α(2)ββ'ω) complexed with a σ factor that is required for promoter-specific transcription initiation. During early elongation, the stability of interactions between σ(70) (the primary sigma factor in Escherichia...

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Hlavní autoři: Nickels, Bryce E., Roberts, Christine W., Roberts, Jeffrey W., Hochschild, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797609/
https://ncbi.nlm.nih.gov/pubmed/17081994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.09.014
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