Synergistic Attenuation of Vesicular Stomatitis Virus by Combination of Specific G Gene Truncations and N Gene Translocations

A variety of rational approaches to attenuate growth and virulence of vesicular stomatitis virus (VSV) have been described previously. These include gene shuffling, truncation of the cytoplasmic tail of the G protein, and generation of noncytopathic M gene mutants. When separately introduced into re...

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Bibliografiska uppgifter
Huvudupphovsmän: Clarke, David K., Nasar, Farooq, Lee, Margaret, Johnson, J. Erik, Wright, Kevin, Calderon, Priscilla, Guo, Min, Natuk, Robert, Cooper, David, Hendry, R. Michael, Udem, Stephen A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797571/
https://ncbi.nlm.nih.gov/pubmed/17151112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-06
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