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Attenuation of Herpes Simplex Virus Neurovirulence with Picornavirus cis-Acting Genetic Elements

Viral pathogenesis depends on a suitable milieu in target host cells permitting viral gene expression, propagation, and spread. In many instances, viral genomes can be manipulated to select for propagation in certain tissues or cell types. This has been achieved for the neurotropic poliovirus (PV) b...

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Bibliografische gegevens
Hoofdauteurs: Campbell, Stephanie A., Mulvey, Matthew, Mohr, Ian, Gromeier, Matthias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797477/
https://ncbi.nlm.nih.gov/pubmed/17079296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00714-06
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