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Resistance of mRNA Translation to Acute Endoplasmic Reticulum Stress-Inducing Agents in Herpes Simplex Virus Type 1-Infected Cells Requires Multiple Virus-Encoded Functions

Via careful control of multiple kinases that inactivate the critical translation initiation factor eIF2 by phosphorylation of its alpha subunit, the cellular translation machinery can rapidly respond to a spectrum of environmental stresses, including viral infection. Indeed, virus replication produc...

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Détails bibliographiques
Auteurs principaux: Mulvey, Matthew, Arias, Carolina, Mohr, Ian
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563692/
https://ncbi.nlm.nih.gov/pubmed/16840316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00479-06
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