The VP35 Protein of Ebola Virus Inhibits the Antiviral Effect Mediated by Double-Stranded RNA-Dependent Protein Kinase PKR

The VP35 protein of Ebola virus is a viral antagonist of interferon. It acts to block virus or double-stranded RNA-mediated activation of interferon regulatory factor 3, a transcription factor that facilitates the expression of interferon and interferon-stimulated genes. In this report, we show that...

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Bibliographic Details
Main Authors: Feng, Zongdi, Cerveny, Melissa, Yan, Zhipeng, He, Bin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797262/
https://ncbi.nlm.nih.gov/pubmed/17065211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01006-06
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