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Cross-priming of cyclin B1, MUC-1 and survivin-specific CD8(+ )T cells by dendritic cells loaded with killed allogeneic breast cancer cells

INTRODUCTION: The ability of dendritic cells (DCs) to take up whole tumor cells and process their antigens for presentation to T cells ('cross-priming') is an important mechanism for induction of tumor specific immunity. METHODS: In vitro generated DCs were loaded with killed allogeneic br...

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Autors principals: Saito, Hiroaki, Dubsky, Peter, Dantin, Carole, Finn, Olivera J, Banchereau, Jacques, Palucka, A Karolina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797030/
https://ncbi.nlm.nih.gov/pubmed/17129372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1621
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