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Dendritic cells loaded with killed breast cancer cells induce differentiation of tumor-specific cytotoxic T lymphocytes

BACKGROUND: Early clinical trials, mostly in the setting of melanoma, have shown that dendritic cells (DCs) expressing tumor antigens induce some immune responses and some clinical responses. A major difficulty is the extension to other tumors, such as breast carcinoma, for which few defined tumor-a...

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Autores principales: Neidhardt-Berard, Eve-Marie, Berard, Frederic, Banchereau, Jacques, Palucka, A Karolina
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC468631/
https://ncbi.nlm.nih.gov/pubmed/15217499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr794
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