Cross-Reactive Neuraminidase Antibodies Afford Partial Protection against H5N1 in Mice and Are Present in Unexposed Humans

BACKGROUND: A pandemic H5N1 influenza outbreak would be facilitated by an absence of immunity to the avian-derived virus in the human population. Although this condition is likely in regard to hemagglutinin-mediated immunity, the neuraminidase (NA) of H5N1 viruses (avN1) and of endemic human H1N1 vi...

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Detalhes bibliográficos
Main Authors: Sandbulte, Matthew R, Jimenez, Gretchen S, Boon, Adrianus C. M, Smith, Larry R, Treanor, John J, Webby, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796909/
https://ncbi.nlm.nih.gov/pubmed/17298168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040059
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