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Dual Stretch Responses of mHCN2 Pacemaker Channels: Accelerated Activation, Accelerated Deactivation

Mechanoelectric feedback in heart and smooth muscle is thought to depend on diverse channels that afford myocytes a mechanosensitive cation conductance. Voltage-gated channels (e.g., Kv1) are stretch sensitive, but the only voltage-gated channels that are cation permeant, the pacemaker or HCN (hyper...

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Detalhes bibliográficos
Main Authors: Lin, Wei, Laitko, Ulrike, Juranka, Peter F., Morris, Catherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796836/
https://ncbi.nlm.nih.gov/pubmed/17142286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.092478
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