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Membrane Stretch Slows the Concerted Step prior to Opening in a Kv Channel

In the simplest model of channel mechanosensitivity, expanded states are favored by stretch. We showed previously that stretch accelerates voltage-dependent activation and slow inactivation in a Kv channel, but whether these transitions involve expansions is unknown. Thus, while voltage-gated channe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laitko, Ulrike, Juranka, Peter F., Morris, Catherine E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151533/
https://ncbi.nlm.nih.gov/pubmed/16735754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509394
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