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Xist and the order of silencing
X inactivation is the mechanism by which mammals adjust the genetic imbalance that arises from the different numbers of gene-rich X-chromosomes between the sexes. The dosage difference between XX females and XY males is functionally equalized by silencing one of the two X chromosomes in females. Thi...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796754/ https://ncbi.nlm.nih.gov/pubmed/17203100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400871 |
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