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The human GINS complex binds to and specifically stimulates human DNA polymerase α-primase
The eukaryotic GINS complex has an essential role in the initiation and elongation phases of genome duplication. It is composed of four paralogous subunits—Sld5, Psf1, Psf2 and Psf3—which are ubiquitous and evolutionarily conserved in eukaryotic organisms. Here, we report the biochemical characteriz...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1796748/ https://ncbi.nlm.nih.gov/pubmed/17170760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400870 |
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