The human GINS complex binds to and specifically stimulates human DNA polymerase α-primase

The eukaryotic GINS complex has an essential role in the initiation and elongation phases of genome duplication. It is composed of four paralogous subunits—Sld5, Psf1, Psf2 and Psf3—which are ubiquitous and evolutionarily conserved in eukaryotic organisms. Here, we report the biochemical characteriz...

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Bibliografiska uppgifter
Huvudupphovsmän: De Falco, Mariarosaria, Ferrari, Elena, De Felice, Mariarita, Rossi, Mosè, Hübscher, Ulrich, Pisani, Francesca M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Scientific Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796748/
https://ncbi.nlm.nih.gov/pubmed/17170760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400870
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